1239 miles, about 18 hr 44 min of driving. Here are the real towns worth stopping in between Des Moines, IA and Myrtle Beach, SC, and why each one earned it.
Named for your own departure time and driving style when you plan the trip — your first full plan is free.
Name every stop — first trip free
No card for the first trip. After that it's 99¢ for three trips, or $2.99 a month.
| Day | Miles | Driving | Night in |
|---|---|---|---|
| 1 | 590 | 8 hr 36 min | Jeffersonville, IN |
| 2 | 577 | 8 hr 38 min | Florence, SC |
| 3 | 72 | 1 hr 30 min | — |
Every stop is a real town on your actual route — not a chain billboard. We score towns on what a driver needs at that point in the drive: fuel and food for a stretch break, parks and grass when a pet is along, hotels and restaurants when it's an overnight. Detour distance counts against a town, so nothing here costs you a long side trip.
This page is planned for a 9-hour driving day leaving at 8:00 AM. Change any of that — your hours, your MPG, pets, small children, an EV's charging range — and the stops change with it. Plan Des Moines to Myrtle Beach your way →
How far is Des Moines, IA to Myrtle Beach, SC?
About 1239 miles, roughly 18 hr 44 min of driving before stops.
Can you drive Des Moines to Myrtle Beach in one day?
Not comfortably. At a 9-hour driving day it splits into 3 days, with a night in Jeffersonville, IN.
Where is a good place to stop between Des Moines and Myrtle Beach?
Walcott, IA is the first one on this route.